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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7150a9562931d5bdf895769c1c5ecf08e52ba5e111612b0b0bf1417e115c2065' 
  AND token = 'GpD/yWCB6enbW0j5qbOrEF+s6NGk6w/Z52el4Q6HXHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}