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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecb4b2ee295bbef131d083dde8f499c0770a2cb8e93eed36c33ce211750af53e' 
  AND token = 'ZLyDkrDCEfS2P3QFCkJwOCVNrMKwd+e3WjkH1Z4IlZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}