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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7856a35a8e7d1bb5caf8b88529eddfb69f22e75e73a5b003e868f6a6f67ce501' 
  AND token = 'KDv5WupvWZTOGyD+1NWK+/Zo2ofd4BBrumf2cKioPxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}