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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb357e551ff4ba3ee43b514a2df6263278fb6348446fc002eb4731a205cbdd7b' 
  AND token = 'tiTXW7TwXnm411RzwhpfdpKdEPnKX9BszeLuj6WINcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}