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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '866eab7e4c29937926da6c5b7b045ca794181362d5f39ba54fbb413345fddef9' 
  AND token = 'yMUwugQDRAq4BIR7DsSB6Qcg7FT3Y3Ph5mAtPyU7bas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}