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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f0cc1b1918b108ddfb8671dfea134a059a268b1b50104cd765104e2824b5b46' 
  AND token = 'wpPkuycScotyW4MOmepEJ3WB6Zr/FW3uDeK2UTQ9p7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}