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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52e4b41d4b35860bd8a4fdaf699241bb9a04c4b56551e87178f534c392cc57f2' 
  AND token = 'fNdYfhRnCRy0Ty7hEEp4OZ6Df6viA2u+xUgsg6JRAcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}