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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a22dbe708f6262460a0155de7685808ed46ce7a6fcc9ce3fb79b0c78ab3382c6' 
  AND token = '7akCIAc9dMpWu83faEWGfuQaeONbHIhpAbTUAgs75GE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}