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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66cc205c04d2a701d528ff46b24198fc1119b41b0539822b5176aed6aada1dc9' 
  AND token = 'egrJxYNBdjH6kKMEgpE638Tf0N0Ghubc3ulsIyOH7EE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}