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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3a5ce407a23c0e19999ba82b164c448092dd57c85db1a1462fc6a9c9c8cb5d2' 
  AND token = 'SQG9S0oBhq30tDsyPtlE8SknTe1FhOROlJxAk9myXEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}