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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8247065cc62b540d4a159e449a9d840581cf6ae1517a4d4d8866648802286a8b' 
  AND token = 'T1KY14ya8jlgpX9M5xJGrT0gO7Z7SrYDrxzdl9D5bXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}