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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35fa095b298407b42a9b2d1f8dd7742ed9fe40827c17f932c0722142f3b8879b' 
  AND token = 'VNP9Qsx+CHCr+SHciPIsLz/OlhA6QGlynLBCVMmVbzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}