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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '045af7be872338d2858dc23c5ce20ac920c2ea7abf34933a8d62ed110ff4e1b5' 
  AND token = 'q/e5tC2uTLvr/cczGpD5SbKvLb1FxGH7JfKtM2bSqcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}