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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fe2f381fcf416b11b1e291cfda5ba0990976c23c89b262e7d55fa0f0dea8f6d' 
  AND token = 'pfTiKiRRuXZ1XyVr3U7u2bMnbMbJPrfeRd/NQnY3KmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}