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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f433f1f8e71d1c09fce6563ee17b634b1bf654a21b02d8bf823c911a1e26e6f2' 
  AND token = 'DC+/odaPXgnTdTQBHELB85VE9zmpsTumMg3rA1vnC+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}