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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7343d58f8726c133acf21020ecb3df8c069daa375c8f45a512d8259e77485041' 
  AND token = 'gZvsKXzQJWY8Jdb4Nuue+FI0OxeNQvFfXzFdMJW9W7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}