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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d08352b20447e23c43ef6f034c05340bc87e7b4df03c39492380332f6e7fc98' 
  AND token = 'AMsxN4y6Y+NQqD/O5fE+A0joMzwsuaXMg8qUcvJNw+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}