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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36b3554288aa9c9408b8cdff844ac30ce86a7a308e52d69c0a4b059e349bd694' 
  AND token = '8oM8/tYP/abvrCHEDFgUVnxAwcYlOdxMt0hdAtLcBds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}