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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50bf5ae2e9231c02d2fc261fb5a2d9afd38c13f70924ec4c9c1fa061239f1349' 
  AND token = 'A8ZU35+a+t9/4OSfiCUT1fGF0yjfUhXrit9oIxvXzSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}