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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c547c60bd316cd30515d74a5c6a2db2570b16160605cc7e396f33d129a2dda44' 
  AND token = 'exldAi48JBmyTElYKRNeUrZkSi9W+w2Vqk+W1GB04LE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}