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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78d3ed6edcaabbd9902a7f6122b152af34e687626082d25224bf6593b9fb91f1' 
  AND token = '4+5GEnaFOmyYOh1xOKgrQqhmdwXxSBjSOw62uyAsBO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}