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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66276c8104c8cf14772bfb5aeea536f78f8c72b1764b89f40cbcbdc150088458' 
  AND token = 'gqtpFOeD77eNuwktB83IVD0WEcdZpB0/jLsZEGvU4hM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}