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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '525fb8fdb076a92b06bb8ecb2d40e8d8f84dd496635f23ab72b2c277a36bb8f8' 
  AND token = 'FtoB1aS54YfAiocosMjmuBF9EdLxx2/UtQckA4Sbk/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}