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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdf1878dc5ac80d62bcbd7b4494f5ac926e14826734077b7867e77c448f0f73b' 
  AND token = 'QFjH/IkqgIUJtFVQzcOiN1HNIWcwp/6E8LtcyzIvcoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}