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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c02bbe6efb32097d73645ddb7e6fb8f82eb4988fca15bad986c137595073dd0' 
  AND token = 'M+JIktGmERFjmE6R4VyWeYs0A0bhQAw3zjBPTn8vt6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}