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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ff0c6de24e833f429e06355a2193063d29cbb582f5401122e39e1d47364769e' 
  AND token = 'czEuZU9x7DRv5RX5DMmyOlFGAsMcKb9epmB3AIWhfeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}