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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e7f1ebec51b7c923b9716de92ed6f041340ad7f3c45401535ed6f4bcfadfd38' 
  AND token = 'fnNmxsI/G3ZuJYnfa0OSZ8c52/w9WiBXnSGZu+c7EMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}