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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35e8d4ec676f9090435d386272d418f7c9f8f741af30f70875f6831664ee3c87' 
  AND token = 'lWEgrRXXEMuqea5x7hQgpjtaqX6XS7D+Bqa5XjEK0gM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}