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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c68f22f5274372be7f325e77d15052f57d767d8360d58259a368e50e67c691e7' 
  AND token = 'YgAL3VH+DETj/u69ovK0sAtCFeQD09K1qxcB0MNsMuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}