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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e62ece37008b4fbfab98dfcabc58d7c74f994b3f9fc026171b3cf701a2f46b67' 
  AND token = 'CoS0yybPjgXHkYWADOJlVih6xExQnsjEDjeA4EC5Qy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}