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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f4128b20afa6291c2a852acf5e6d45f50dab78dc711f2bf415befa4b36974e5' 
  AND token = 't0NdUVsh7E3TkDVwk5ryc82SPAsJHiuQopHRHgJJG2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}