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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01d7523742991a7d022720eccdde4517772ce3bc944e3450136bfc8a216b2e7c' 
  AND token = 'pySbIQ3ULmc3dSUX+C7IG+d27ryPch2oVj3wkD8czcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}