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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '277306934843091a3f75f2fc1449ee481c22d3d0fe3f5312b83a30dd0a2faf1f' 
  AND token = '9aQQZbcIc8IxX2kUN/kgFX+JhiWyCIE1BU1VL0xSzcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}