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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5ab9da0a6a417e871b4c3e1fb6b6d36043936679f79768732fdad58ff08f605' 
  AND token = 's0+NCt+tCdSwI612Tguvg1ETEoOsnJbsvvmASIfcqdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}