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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b43ece105378f65392c96a007a6c12e987eaf1b7e4afd60a2b4fde386499d43' 
  AND token = 'BSJrrcLO3dcw/4qibh2+Au/WAMeUbwdbE2/DcasU5Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}