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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afe11ad6bd105307ad4178fa933dba5b9c599e4ba5fb7fe8e4e3828e020b72c1' 
  AND token = 'zEAbeMrVY4jeD8NAQ9i7fso/97ZWwBxKuUTKWHBEa1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}