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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a0ed0fe704bbd94e7a78b2d23c5635d34bbebaac4216ca17df64669b3736b61' 
  AND token = 'gFUOSgV17MuczW8Y+lbcAO9hcIvl2mgu0dlu723ZnsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}