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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed6e1456db763497a1f2515df6c87417bc2beca3e9aba0544212ff18e88c214e' 
  AND token = 'wS8J8O+9IDWPumW6QZdaaRZfgC2UY7Vt548kpRUTaKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}