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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ef8ad59c0aae53d898a3d4c22c068fb06e19b03dc25a370191c058ff79459c9' 
  AND token = 'BZcUNw3CLwzE/yL3MZWsJSfmLQ4sHJxrYZUEt+8o2C4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}