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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc048296b8101994d6ac7579f539e77de438e950885f1c502ee8354250b26aed' 
  AND token = 'obLLRRPxN3dftZfW5AT7l8p++/3+DXbdgOh4p5Z6v0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}