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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66749147fc8608913850a6c5ca1faadc23d03d15b11e5bb79339e7362a75d1a9' 
  AND token = 'F10jH6109KDPym+JX/3tgARt9YyggLgmTykbofMd8Zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}