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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35b30aecc9eea6ddb8ca35b8faeb8e61713cbf7e846ba198521becc7fdc3b180' 
  AND token = 'F6VwKtkDSbfAFOtBKnzsj74xy/SlWtbB8HHu8AYPGk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}