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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04ae6527cfb46ab1ab4aa5ec0a952c16a4f031c637b3337f6280607bd8227e8f' 
  AND token = 'XrT1yno3bAoX43zlITOKzueQkmPEtSNoEoyOqxBZpY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}