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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecea3f6f8868aefef8f5df65d3dc25f03f7cec6f389599dfa6ac5295f0e83187' 
  AND token = 'LiOGEhRgU57gaU2KPsdnrwWlYfOLwA8Jjw0zu3BjlUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}