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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '96b8f8da959ec6b921c72b05c2eedb5b3a78e651d51545eccfe5d395266fe423' 
  AND token = '2IuWEPs8my0PpKGN92j3jwwmZ3jDIpq58GW1FM2dq8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}