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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6678b2bddfa45210f7fa10cf350cf5697a39ecc630c656ef7a0aa477d15edcc6' 
  AND token = '9Dp3y4R246NksLo8c8z6DFpuH1WD9TxxUVpUE6JXkcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}