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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b605f9781f7a5b4a113e1f25499fd0fe74ac292f629e410580305d4985f026d9' 
  AND token = 'SsvLY1MkREex5agL89Xm4+Phmqbrqq1gwNYh+BLxXQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}