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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0e0fe3d2f8ff99fd8ffe46ac0cacf1eb0a1ee675836e72170b891e12aa3948d' 
  AND token = 'CPwM1yaZPwv1jOZE15MIargo/Uk3syKxSIZY06ismas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}