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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72bf1a127133772595ebcf79b0fcd7be0828a8c99a9f7c7b110cfcc4e9785f01' 
  AND token = 'YpeYsWCvkaGx8nxlMaAtxDdzwxi9u5Quta90JztzE3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}