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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd78eabe9f21d355b2f1c2e787cf94343b8bd411d874e0eb3e122d89aaa4c7450' 
  AND token = 'eaiq7Gcs0k0RtZ5yvNK6gnRx30CuaBzRTH9evyNaFEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}